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Riesgo cardiovascular en pacientes con esclerosis sistémica
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Chico Capote, Araceli

; Estévez del Toro, Miguel Hernán

; Cruz Cárcamo, Orlando Antonio

; Puente Carmona, Rolando

Revista Cubana de Medicina

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2024, Volume 63 elocation e3408

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: Cardiovascular risk is important in the evaluation of patients with systemic sclerosis. Objective: To determine the cardiovascular risk in patients with systemic sclerosis. Methods: A cross-sectional and descriptive study was carried out in protocolized patients of Rheumatology Service, from January 2020 to January 2022. Demographic and clinical variables were collected, and Framingham cardiovascular risk calculator was used. Results: One hundred five patients were included with a mean age of 48.6 ± 15.3 years, the most frequent group was 50 to 59 years (36.2%), female sex (92.2%) predominated, as well as white skin color (74.3%). The evolution time was greater than 5 years (66.7%) with a mean of 10.5 ± 9.3. The average value of modified Medsger severity scale was 5.1 ± 2.7 and 72.4% had mild involvement. Raynaud's phenomenon and pulmonary fibrosis were more common at 89.5% and 55.2%. Rodnan index on average was 13.1 ± 8.0 and the acute phase reactants were normal in the majority. The most frequent cardiovascular risk factors were HBP (30.2%) and dyslipidemia (19.9%). The predominant body mass index was adequate weight (54.3%). Low cardiovascular risk according to Framingham score prevailed (86%). There were significant differences between the mean duration of evolution and cardiovascular risk (10 ± 6.9 vs. 9.6 ± 8.8 vs. 16.9 ± 10.8; p = 0.032). Conclusions: The cardiovascular risk in patients with systemic sclerosis was low.

RESUMEN Introducción: El riesgo cardiovascular es importante en la evaluación de los pacientes con esclerosis sistémica. Objetivo: Determinar el riesgo cardiovascular en pacientes con esclerosis sistémica. Métodos: Se realizó un estudio transversal y descriptivo en pacientes protocolizados del Servicio de Reumatología, en el período de enero 2020 a enero 2022. Se recogieron variables demográficas, clínicas, y se aplicó la calculadora de riesgo cardiovascular Framingham. Resultados: Se incluyeron 105 pacientes con edad media de 48,6 ± 15,3 años, el grupo más frecuente de 50 a 59 años (36,2 %), predominó el sexo femenino 92,2 % y el color de piel blanca (74,3 %), el tiempo de evolución fue mayor a 5 años (66,7 %) con una media de 10,5 ± 9,3. El valor promedio de la escala de gravedad modificada de Medsger fue 5,1 ± 2,7 y el 72,4 % con afectación leve. El fenómeno de Raynaud y la fibrosis pulmonar fueron más frecuentes con un 89,5 % y 55,2 %. El índice de Rodnan en promedio fue de 13,1 ± 8,0 y los reactantes de fase aguda normales en la mayoría. Los factores de riesgo cardiovascular más frecuentes fueron la HTA (30,2 %) y dislipidemia (19,9 %). El índice de masa corporal que predominó fue de peso adecuado (54,3 %). Predominó el riesgo cardiovascular bajo según score de Framingham (86 %). Existieron diferencias significativas entre las medias del tiempo de evolución y el riesgo cardiovascular (10 ± 6,9 frente a 9,6 ± 8,8 frente a 16,9 ± 10,8; p = 0,032). Conclusiones: El riesgo cardiovascular en los pacientes con esclerosis sistémica fue bajo.

Posicionamento do Departamento de Imagem Cardiovascular da Sociedade Brasileira de Cardiologia sobre o Uso do Strain Miocárdico na Rotina do Cardiologista – 2023
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Almeida, André Luiz Cerqueira

; Melo, Marcelo Dantas Tavares de

; Bihan, David Costa de Souza Le

; Vieira, Marcelo Luiz Campos

; Pena, José Luiz Barros

; Del Castillo, José Maria

; Abensur, Henry

; Hortegal, Renato de Aguiar

; Otto, Maria Estefania Bosco

; Piveta, Rafael Bonafim

; Dantas, Maria Rosa

; Assef, Jorge Eduardo

; Beck, Adenalva Lima de Souza

; Santo, Thais Harada Campos Espirito

; Silva, Tonnison de Oliveira

; Salemi, Vera Maria Cury

; Rocon, Camila

; Lima, Márcio Silva Miguel

; Barberato, Silvio Henrique

; Rodrigues, Ana Clara

; Rabschkowisky, Arnaldo

; Frota, Daniela do Carmo Rassi

; Gripp, Eliza de Almeida

; Barretto, Rodrigo Bellio de Mattos

; Silva, Sandra Marques e

; Cauduro, Sanderson Antonio

; Pinheiro, Aurélio Carvalho

; Araujo, Salustiano Pereira de

; Tressino, Cintia Galhardo

; Silva, Carlos Eduardo Suaide

; Monaco, Claudia Gianini

; Paiva, Marcelo Goulart

; Fisher, Cláudio Henrique

; Alves, Marco Stephan Lofrano

; Grau, Cláudia R. Pinheiro de Castro

; Santos, Maria Veronica Camara dos

; Guimarães, Isabel Cristina Britto

; Morhy, Samira Saady

; Leal, Gabriela Nunes

; Soares, Andressa Mussi

; Cruz, Cecilia Beatriz Bittencourt Viana

; Guimarães Filho, Fabio Villaça

; Assunção, Bruna Morhy Borges Leal

; Fernandes, Rafael Modesto

; Saraiva, Roberto Magalhães

; Tsutsui, Jeane Mike

; Soares, Fábio Luis de Jesus

; Falcão, Sandra Nívea dos Reis Saraiva

; Hotta, Viviane Tiemi

; Armstrong, Anderson da Costa

; Hygidio, Daniel de Andrade

; Miglioranza, Marcelo Haertel

; Camarozano, Ana Cristina

; Lopes, Marly Maria Uellendahl

; Cerci, Rodrigo Julio

; Siqueira, Maria Eduarda Menezes de

; Torreão, Jorge Andion

; Rochitte, Carlos Eduardo

; Felix, Alex

Arquivos Brasileiros de Cardiologia

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Dez 2023, Volume 120 Nº 12 elocation e20230646

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.36660/abc.20230646

Introgression of transgenic events and accompanying sequences into Mexican maize varieties
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Siller-García, Jessica Nallely

; Cruz-González, Miguel Ángel

; Castillo-Reyes, Francisco

; Rodríguez-Herrera, Sergio Alfredo

; Morlett-Chávez, Jesús Antonio

; Aguilar, Cristóbal N.

; Rodríguez-Herrera, Raúl

Ecosistemas y recursos agropecuarios

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Ago 2023, Volume 10 Nº 2 elocation e3538

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen: Se recolectaron muestras de semillas de 215 de variedades de maíz representativas de cuatro (Jalisco, Michoacán, Oaxaca y Puebla) estados de México. El total de genotipos colectados en cada Estado fue de 53, 96, 46 y 20, respectivamente. Cada colecta de semilla fue georreferenciada; posteriormente cada colecta se sembró y el tejido foliar se usó para el aislamiento de ADN, luego se realizó un análisis de PCR para determinar la presencia o ausencia de ocho secuencias acompañantes y nueve eventos transgénicos en los 215 genotipos. Los resultados mostraron la introgresión de secuencias acompañantes y eventos transgénicos (cry1Ab) en el genoma de algunas variedades locales de maíz. La mayor proporción de residuos de cry1Ab observados en las variedades locales de maíz fue la muestra de Puebla (70%), seguida por las muestras de Oaxaca donde se observó 52%, mientras que 15 y 7.5% de los maíces nativos del estado de Jalisco presentaron el gen cry1Ab y la secuencia acompañante ntpII, respectivamente. Las muestras de Michoacán mostraron 44 y 17.7% para el gen cry1Ab y la secuencia acompañante, respectivamente. Estos resultados deben respaldar la aplicación de medidas correctivas para prevenir la contaminación genética de variedades locales de maíz y limpiar fenotipos fuera de tipo que podrían ser fuentes de contaminación de genes transgénicos dentro de poblaciones de variedades locales de maíz contaminadas con estos transgenes.

Abstract Representative seed samples of 215 of maize varieties from four (Jalisco, Michoacán, Oaxaca and Puebla) Mexican States were collected. The total genotypes collected in each State were 53, 96, 46 and 20 samples, respectively. Each seed collection was geo-referenced, then seed was planted and leaf tissue was used for DNA isolation, after that a PCR analysis was performed to determine the presence or absence of eight accompanying sequences and nine transgenic events in the 215 maize genotypes. Results showed introgression of accompanying sequences and transgenic events (cry1Ab) into some maize varieties. The major proportion of cry1Ab residues was observed in maize samples from Puebla (70%) followed by that displayed in the Oaxaca samples (52%), while Jalisco samples showed 15 and 7.5% of the cry1Ab gene and ntpII accompanying sequence, respectively, and Michoacán samples exhibited 44 and 17.7% for cry1Ab gene and the accompanying sequence, respectively. These results supported for applicate corrective measures for to prevent the genetic contamination of Mexican maize varieties and to clean up out-of-type phenotypes that could be sources of contamination of transgenic genes within maize populations contaminated with transgenes.

https://doi.org/10.19136/era.a10n2.3538

Antagonismo de cepas de Trichoderma aisladas en Tanaxuri, Michoacán, México contra patógenos postcosecha del fruto de aguacate (Persea americana Mill)
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López-López, María Estela

; Toro-Sánchez, Carmen Lizette Del

; Ochoa-Ascencio, Salvador

; Aguilar-López, José Antonio

; Martínez-Cruz, Oliviert

; Madrigal-Pulido, Jaime Alberto

; Robles-García, Miguel Angel

; Bernal-Mercado, Ariadna Thalia

; Ávila-Novoa, María Guadalupe

; Guerrero-Medina, Pedro Javier

; Gutiérrez-Lomelí, Melesio

Biotecnia

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Abr 2023, Volume 25 Nº 1 Páginas 24 - 33

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen Algunas especies del género Trichoderma poseen la capacidad de parasitar hongos patógenos de plantas. Esta característica propicia un alto potencial de uso en el control de las enfermedades (antracnosis) causadas por hongos en el fruto de aguacate postcosecha. Por lo tanto, el objetivo de esta investigación fue el aislamiento e identificación de cepas nativas de Trichoderma de cultivos de aguacate con potencial antagonista in vivo e in vitro contra patógenos de este fruto. Las cepas fueron aisladas de raíz y suelo del huerto de aguacate en la localidad de Tanaxuri, Michoacán. Se obtuvieron seis cepas y se caracterizaron como TSONM1 (Trichoderma spp.), TRONM2 (Trichoderma spp.), TSONM3 (Trichoderma spp.), TSONM4 (Trichoderma spp.), TSONM5 (Trichoderma spp.) y TSONM6 (Trichoderma harzianum). Posteriormente, las cepas aisladas fueron confrontadas con Neofusicoccum parvum, Colletotrichum gloeosporioides, Diaporthe sp. y Phomopsis perseae observándose inhibiciones in vitro mayores al 80 %. Mientras que en la evaluación in vivo, la cepa TSONM6 (Trichoderma harzianum) presentó mayor actividad antagónica contra C. gloeosporioides, Diaporthe sp. y P. persea. Adicionalmente, los frutos de aguacate tratados con TSONM6, presentaron mínimos porcentajes (< 2 %) de pudrición de la pulpa y pedúnculo. Por lo tanto, Thichoderma harzianun podría ser una buena alternativa para el control biológico del aguacate en postcosecha.

Abstract Some species of the genus Trichoderma have the ability to parasitize fungal plant pathogens. This characteristic provides a high potential for use in the control of diseases (anthracnose) caused by fungi in post-harvest avocado fruit. Therefore, the objective of this research was the isolation and identification of native Trichoderma strains from avocado cultures with antagonistic potential in vivo and in vitro against pathogens of this fruit. The strains were isolated from the root and soil of the avocado in the town of Tanaxuri, Michoacán. Six strains were obtained and characterized as TSONM1 (Trichoderma spp.), TRONM2 (Trichoderma spp.), TSONM3 (Trichoderma spp.), TSONM4 (Trichoderma spp.), TSONM5 (Trichoderma spp.) and TSONM6 (Trichoderma harzianum). Subsequently, the isolated strains were confronted with Neofusicoccum parvum, Colletotrichum gloeosporioides, Diaporthe sp. and Phomopsis perseae, observing in vitro inhibitions greater than 80 %. In the in vivo evaluation, the TSONM6 strain (Trichoderma harzianum) showed greater antagonistic activity against C. gloeosporioides, Diaporthe sp. and P. persea. Additionally, the avocado fruits treated with TSONM6, presented minimum percentages (< 2 %) of pulp and peduncle rotting. Therefore, Thichoderma harzianun could be a good alternative for postharvest biological control of avocado.

https://doi.org/10.18633/biotecnia.v25i1.1726

Sociodemographic inequalities in cardiovascular risk factors among adolescents from indigenous areas in Chiapas, Mexico
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Flores-Guillén, Elena

; Castro-Quezada, Itandehui

; Irecta-Nájera, César Antonio

; Núñez-Ortega, Pilar E.

; Solís-Hernández, Roberto

; García-Miranda, Rosario

; Cruz-Cruz, Paola

; Medina-Gómez, Christian

; Sánchez-Chino, Xariss M.

; Olivo-Vidal, Zendy Evelyn

; Cruz, Miguel

; Ochoa-Díaz-López, Héctor

Cadernos de Saúde Pública

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2023, Volume 39 Nº 11 elocation e00024623

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo: O objetivo deste estudo foi determinar a prevalência de fatores de risco cardiovascular entre diferentes grupos sociodemográficos de adolescentes de comunidades indígenas em Chiapas, México. Foi realizado um estudo transversal de prevalência em comunidades urbanas e rurais das regiões de Tzotzil-Tzeltal e Selva de Chiapas. Foi estudada uma amostra de 253 adolescentes, sendo 48% meninas e 52% meninos. Foi realizada uma análise descritiva das variáveis quantitativas por meio de medidas de tendência central e dispersão. Foram estimadas as prevalências de fatores de risco cardiovascular, estratificadas por sexo, área geográfica, escolaridade e etnia das mães. A prevalência dos fatores de risco cardiovascular foi analisada em relação às características sociodemográficas da população estudada. O HDL-c baixo (51%) foi o fator de risco cardiovascular predominante. Prevalências mais elevadas de obesidade abdominal, hipertrigliceridemia e colesterol total limítrofe foram mais observadas em meninas do que em meninos. A pressão arterial diastólica elevada prevaleceu nos meninos. Adolescentes da área urbana apresentaram prevalências de sobrepeso/obesidade e resistência à insulina maiores do que os da área rural. A prevalência de sobrepeso/obesidade e obesidade abdominal foi maior nos adolescentes cujas mães possuíam escolaridade ≥ 7 anos do que naqueles indivíduos cujas mães tinham baixa escolaridade. As diferenças de etnia das mães também foram observadas na prevalência de resistência à insulina. Dentre as principais conclusões, foram encontradas, neste estudo, desigualdades sociodemográficas e geográficas entre fatores de risco cardiovascular. Promover estilos de vida saudáveis entre a população jovem é o ideal para prevenir doenças cardiovasculares na vida adulta.

Abstract: This study was aimed to determine the prevalence of cardiovascular risk factors among different sociodemographic groups of adolescents from indigenous communities in Chiapas, Mexico. A cross-sectional prevalence study was performed in urban and rural communities in the Tzotzil-Tzeltal and Selva regions of Chiapas. A sample of 253 adolescents was studied, of whom 48% were girls and 52% were boys. A descriptive analysis of quantitative variables was performed using measures of central tendency and dispersion. The prevalence of cardiovascular risk factors stratified by sex, geographical area, years of schooling, and ethnicity of the mothers was estimated. The prevalence of cardiovascular risk factors was analyzed in relation to the sociodemographic characteristics of the study population. Low HDL-c (51%) was the predominant cardiovascular risk factor. Girls had a higher prevalence of abdominal obesity, hypertriglyceridemia, and borderline total cholesterol than boys. High diastolic blood pressure was more prevalent in boys. Adolescents from urban areas had a higher prevalence of overweight/obesity and insulin resistance than adolescents from rural areas. The prevalence of overweight/obesity and abdominal obesity was higher in adolescents whose mothers had ≥ 7 years of schooling compared with adolescents with less educated mothers. Differences by maternal ethnicity also influenced the prevalence of insulin resistance. Among the main findings, this study associated sociodemographic and geographical inequalities with cardiovascular risk factors. Promoting a healthy lifestyle for this young population is absolutely necessary to prevent cardiovascular diseases in adulthood.

Resumen: El objetivo de este estudio fue estimar la prevalencia de los factores de riesgo cardiovascular entre diferentes grupos sociodemográficos de adolescentes de comunidades indígenas de Chiapas, México. Se realizó un estudio transversal de prevalencia en comunidades urbanas y rurales de las regiones Tzotzil-Tzeltal y Selva, en Chiapas. Participó una muestra de 253 adolescentes, en la cual el 48% eran niñas y el 52% niños. Se realizó un análisis descriptivo de las variables cuantitativas utilizando medidas de tendencia central y dispersión. Se estimó la prevalencia de los factores de riesgo cardiovascular, estratificados por sexo, área geográfica, nivel de estudios y etnia de las madres. Se analizó la prevalencia de los factores de riesgo cardiovascular con relación a las características sociodemográficas de la población estudiada. El HDL-c bajo (51%) fue el factor de riesgo cardiovascular predominante. Se observó una mayor prevalencia de obesidad abdominal, hipertrigliceridemia y colesterol total en las niñas que en los niños. La alta presión arterial diastólica prevaleció en los niños. Los adolescentes del área urbana tuvieron una mayor prevalencia de sobrepeso/obesidad y resistencia a la insulina que los del área rural. La prevalencia de sobrepeso/obesidad y obesidad abdominal fue mayor en los adolescentes cuyas madres tenían nivel de estudios ≥ 7 años que aquellos cuyas madres tenían bajo nivel de estudios. Las diferencias en la etnicidad materna también influyeron en la prevalencia de resistencia a la insulina. Entre las principales conclusiones de este estudio, se destacan las desigualdades sociodemográficas y geográficas entre los factores de riesgo cardiovascular. La promoción de un estilo de vida saludable entre la población joven es lo indicado para prevenir las enfermedades cardiovasculares en la edad adulta.

https://doi.org/10.1590/0102-311xen024623

Gestational monitoring in buffalo females: detection of Neospora caninum by PCR
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Reyes-Sandoval, Raúl Miguel

; Romero-Salas, Dora

; Chaparro-Gutiérrez, Jenny Jovanna

; Cruz-Romero, Anabel

; López-Hernández, Karla María

; Lammoglia-Villagómez, Miguel Ángel

; González-Hernández, Milagros

; Alarcón-Zapata, Marco Antonio

; Vergara-Reyes, Rebeca Isabel

Animal Reproduction

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2023, Volume 20 Nº 4 elocation e20230052

Resumo: En | Texto: En | PDF: En

Abstract This study establishes the serological frequency against Neospora caninum on day zero and the presence of N. caninum DNA surveyed throughout the gestation of Bubalus bubalis females in a bovine buffalo system in the central zone of the state of Veracruz, Mexico. Blood samples were taken from 11 females in 6 different sampling periods and analyzed for N. caninum antibodies detection on day zero. DNA detection by PCR was performed on all sampling periods. The gestation months of the females were recorded for five trimesters by ultrasonography, as well as births and pregnancy losses. Recorded seropositivity and positivity for agent DNA were 90.9% (95% CI 58.7-9.7) and 36.3% (95% CI 10.9-69.2), respectively, on day zero. N. caninum DNA was detected between 18.1% (95% CI 2.3-51.7) and 45.4% (95% CI 16.7-76.6) over the five trimesters of observation, with three births and three abortions recorded. The studied water buffalo population had a high presence of N. caninum antibodies; however, the detection of N. caninum DNA remained below 47% in the females. The association was only observed in the detection of DNA with pregnant females (P 0.007). Our results support the hypothesis of the resistance of water buffaloes to infection and the onset of clinical signs against infection by N. caninum even upon a high possibility of infection and reinfection described in this production system in Mexico.

https://doi.org/10.1590/1984-3143-ar2023-0052

Sociodemographic inequalities in cardiovascular risk factors among adolescents from indigenous areas in Chiapas, Mexico
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Flores-Guillén, Elena

; Castro-Quezada, Itandehui

; Irecta-Nájera, César Antonio

; Núñez-Ortega, Pilar E.

; Solís-Hernández, Roberto

; García-Miranda, Rosario

; Cruz-Cruz, Paola

; Medina-Gómez, Christian

; Sánchez-Chino, Xariss M.

; Olivo-Vidal, Zendy Evelyn

; Cruz, Miguel

; Ochoa-Díaz-López, Héctor

Cadernos de Saúde Pública

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2023, Volume 39 Nº 11 elocation e00024623

Resumo: En Es Pt | Texto: En Es Pt | PDF: En | PDF: Es | PDF: Pt

https://doi.org/10.1590/0102-311xen024623

Laparoscopic nephrectomy in patients with renal exclusion secondary to urolithiasis. Which factors can predispose conversion to open surgery?
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Cueto-Vega, Guillermo J.

; Basulto-Martinez, Mario J.

; Esqueda-Mendoza, Antonio

; Cruz-Nuricumbo, Eduardo

; Flores-Tapia, Juan P.

; Bastarrachea-Solis, Michel A.

; Monzon-Falconi, Juan F.

; Equihua-Sánchez, Miguel

Cirugía y cirujanos

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Ago 2022, Volume 90 Nº 4 Páginas 454 - 458

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Background: The prevalence of urolithiasis is 7-10% and has increased over the past years. Simple nephrectomy is, therefore, indicated when renal exclusion is associated with recurrent urinary tract infections and/or chronic pain. Objective: The aim of the study was to describe the surgical experience of laparoscopic nephrectomy (LPN) due to urolithiasis in Mexican South-east and which factors can predispose conversion to open surgery. Methods: This was a retrospective study including patients with renal exclusion secondary to urolithiasis, who underwent laparoscopic simple nephrectomy between 2016 and 2019. Results: Forty simple LPN for renal exclusion due to urolithiasis was performed between 2016 and 2019. Mean age was 47 ± 10.8 and 82.5% were female. The mean BMI was 30.2 ± 5 kg/m2, mean operative time was 165.2 ± 64. Conversion rate was 12.5% (n = 5). Conversion was significantly associated with abnormal hilum vascular anatomy (p = 0.001), hilum adherences (p = 0.001), and hydronephrosis (p = 0.001). Conclusion: LPN is a safe surgical technique for renal exclusion due to urolithiasis. Hydronephrosis, abnormal vascular anatomy, and the adherences that involved de hilum are the factors that could predictive conversion to open surgery.

Resumen Introducción: La prevalencia the urolitiasis es del 7-10% sin embargo a presentado un incremento del numero de casos en los ultimos años. La nefrectomia simple laparoscopica esta indicada en pacientes con exclusión renal asociado a cuadros repetitivos de infecciones en el tracto urinario y o dolor cronico a nivel fosa renal. Objetivo: Describir la experiencia de nefrectomia simple laparoscopica en pacientes con exclusion renal secundario litiasis en un hospital del sur de México, y que factores pueden predisponer la conversión a cirugia abierta. Materials y metodos: Estudio restrospectivo que incluyo pacientes con exclusion renal secundario a urolitiasis durante el periodo comprendido entre 2016 y 2019. Resultados: Se realizaron 40 nefrectomias simples laparoscopica durante el periodo comprendido 2016 y 2019 en paciente con exclusion renal asociada a litiasis. La media edad 47 ± 10.8 años, el 82.5% de los pacientes fueron del sexo femenino. La media de Indice de masa corporal fue de 30.2 ± 5 kg/m2, La tasa de conversion fue del 12.5% (n = 5), los factores que se asociaron a conversion a cirugia abierta fueron anormalidades dependientes del hilio vascular renal (p = 0.001)., adherencias dependientes del hilio renal (p = 0.001). e hidronefrosis (p = 0.001). Conclusión: La nefrectomia simple laparocopica es un procedimiento seguro en pacienres con exclusion renal secundaria a urolitiasis. Hidronefrosis, anormalidades dependientes del hilio vascular renal y adherencias que involucren el hilio renal son factores que pueden predisponer conversion a cirugia abierta.

https://doi.org/10.24875/ciru.20001397 35 downloads

Síndrome de vena cava superior por trombosis de catéter venoso central, Caso Clínico.
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Labrín, Marco Antonio Vergara

; Cruz, Miguel Angel Guevara

; Salazar, Hernán Aste

; Salazar, Aurelio Napoleón Delgado

Revista de la Facultad de Medicina Humana

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Jul 2022, Volume 22 Nº 3 Páginas 637 - 641

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

RESUMEN Introducción: El síndrome de vena cava superior es una entidad poco frecuente en la literatura. Caso Clínico: Presentamos el caso de paciente masculino, 32 años, que consulta al servicio de emergencia por cianosis facial súbita, opresión en rostro, tos seca, odinofagia, disfonía; sin referir disnea. Al examen físico: edema en esclavina, cianosis central, petequias y sangrado ungueal en manos. Antecedente de neoplasia de colón, con colostomía y colocación de catéter Port subclavio izquierdo hace 2 años. La angiotomografia muestra defecto de llenado por trombosis reciente en venas yugular interna, braquiocefálica izquierda y derecha, arco de la ácigos y cava superior en toda su luz. La patología neoplásica asociada a procedimientos invasivos con catéter venosos centrales elevan el riesgo de presentación, como nuestro caso, con una obstrucción venosa completa intrínseca severa. El tratamiento quirúrgico con trombectomía por aspiración mecánica permitió la resección total del trombo y restitución integral de la circulación.

ABSTRACT Introduction: Superior vena cava syndrome is a rare entity in literature. Clinical Case: We present the case of a 32-year-old male patient who visited the Emergency Department due to sudden facial cyanosis, facial pressure, dry cough, odynophagia, and dysphonia, without reporting dyspnea. On physical examination: face, neck, and supraclavicular region edema, central cyanosis, petechiae, and subungual haemorrhage in the hands. History of colon neoplasia, with colostomy and placement of a left subclavian Port catheter 2 years ago. CT angiography shows a filling defect due to recent thrombosis in the internal jugular veins, left and right brachiocephalic veins, arch of the azygos, and superior vena cava in all its lumen. Neoplastic pathology associated with invasive procedures with central venous catheters increases the risk of presentation, as in our case, with severe intrinsic complete venous obstruction. Surgical treatment with thrombectomy by mechanical aspiration allowed total resection of the thrombus and full restoration of circulation.

https://doi.org/10.25176/rfmh.v22i3.4323

10.

Fatores que influenciam a escolha do contracetivo na mulher
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Cunha, Rebeca de Sousa e

; Ferreira, António Cruz

; Santiago, Luiz Miguel

Revista Portuguesa de Medicina Geral e Familiar

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Fev 2022, Volume 38 Nº 1 Páginas 34 - 46

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Introdução: A escolha do método contracetivo da mulher em idade fértil é determinada por um conjunto de receios e condicionalismos. Objetivos: Identificar fatores que condicionam a escolha do método contracetivo num grupo de mulheres em idade fértil e discutir possíveis estratégias a utilizar pelo médico de família, promovendo uma escolha esclarecida. Métodos: Inicialmente realizou-se uma revisão da literatura, através de pesquisa na PubMed, circunscrita ao período entre 2010 e 2019, utilizando a equação: contraception OR family planning AND selection criteria. Posteriormente realizou-se um estudo observacional, descritivo, em setembro de 2019, em três USF da região centro de Portugal. As mulheres em idade fértil, com consulta programada de planeamento familiar, foram a população alvo. A amostra foi selecionada aleatoriamente (n=127). Responderam a um questionário que permitiu recolher dados pessoais, como idade, estado civil e número de partos e gravidezes, e a sua avaliação quantitativa relativamente a uma lista de fatores que poderiam influenciar a decisão sobre a escolha do método contracetivo. Resultados: O contracetivo hormonal oral foi o método mais utilizado pelas participantes (57,5%), enquanto a segurança (78,7%) e a eficácia do método (78%) foram os fatores considerados mais importantes. Com menor destaque, as mulheres referiram: facilidade no uso/aplicação (59,8%), evitar perdas sanguíneas irregulares (55,9%), proteger contra doenças sexualmente transmissíveis (54,3%), acessibilidade (53,5%) e evitar efeitos colaterais (53,5%). Quanto à opinião de terceiros, apenas a opinião do médico foi considerada muito importante para 59,1% delas. Conclusão: Este estudo permitiu identificar os fatores considerados relevantes para as mulheres em idade fértil no momento da escolha do seu contracetivo. Estes resultados poderão auxiliar os médicos de família a direcionar a sua abordagem, dando resposta às suas dúvidas e inquietações para que, posteriormente, estas possam decidir sobre o método a utilizar.

Abstract Introduction: The choice of contraceptive method in women of childbearing age is accompanied by a set of fears and constraints. Objectives: To identify factors that influence the choice of contraceptive method, in a group of women of childbearing age and discuss possible strategies to be used by the family physician, aiming at an informed choice. Methods: Firstly, a literature review was performed by searching the PubMed electronic database, limited to the period between 2010 and 2019, using the key: ‘contraception’ OR ‘family planning’ AND ‘selection criteria’. Subsequently, an observational and descriptive study was conducted in September 2019 in three Family Health Units in central Portugal. Women of childbearing age, with scheduled family planning consultation, were the target population. The sample was randomly selected (n=127). These women answered a questionnaire that allowed the collection of personal data such as age, marital status, and prior pregnancies, as well as their quantitative assessment against a list of factors that could influence their decision about the choice of a contraceptive method. Results: The oral hormonal contraceptive was the most used method (57.5%), while the effectiveness (78%) and safety of the method (78.7%) were considered very important factors. Less prominently, women reported the following factors: ease of use (59.8%), preventing irregular blood loss (55.9%), protecting against sexually transmitted diseases (54.3%), accessibility (53.5%), and avoiding side effects (53.5%). Regarding the opinion of third parties, only the opinion of the doctor was considered very important for 59.1% of them. Conclusion: This study allowed the identification of a set of factors considered relevant for women of childbearing age when choosing a contraceptive method. These results may help family physicians direct their approach, answering their questions and concerns so that later they can make their individual decision on which method to use.

https://doi.org/10.32385/rpmgf.v38i1.13142 30 downloads

11.

Comprando qualidade: costume, gosto e reciprocidade nas feiras livres do Vale do Jequitinhonha
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Cruz, Maria Sirlene da

; Ribeiro, Eduardo Magalhães

; Perondi, Miguel Angelo

; Araujo, Alexandro Moura

; Maltez, Marcos Antonio Pereira da Fonseca

Revista de Economia e Sociologia Rural

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2022, Volume 60 Nº spe elocation e245926

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Este artigo analisa cinco feiras livres que abastecem uma parte substancial da população urbana do Alto Jequitinhonha na contramão do sistema agroalimentar dominante. Usando dados de fontes primárias e secundárias, são analisadas as relações estabelecidas entre consumidores e vendedores – os quais, em sua maioria, são agricultores – para interpretar as dimensões culturais e econômicas do abastecimento das pequenas cidades. O resultado da pesquisa indica que as feiras se relacionam com a identidade cultural alimentar, o abastecimento de grande parte da população urbana e movimenta parte expressiva da economia local dos municípios.

Abstract This article analyzes five open fairs that supply a substantial part of the urban population of Alto Jequitinhonha in opposition to the dominant agri-food system. Based on primary and secondary data, the relationships between consumers and sellers are analyzed - mostly family farms – to interpret the cultural and economic dimensions of supply in small towns. The results of this research indicate that the fairs are related to food cultural identity, to the supply of the urban population, and move an expressive part of the local economy of the municipalities.

https://doi.org/10.1590/1806-9479.2021.245926 86 downloads

12.

Sistemas silvopastoriles enriquecidos: una propuesta para integrar la conservación en la producción ganadera en comunidades rurales de Los Tuxtlas, México
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Peña-Domene, Marines de la

; Ayestarán Hernández, Luz María

; Márquez Torres, José Flavio

; Martínez Monroy, Fernando

; Rivas Alonso, Edith

; Carrasco Carballido, Patricia Valentina

; Pérez Cruz, Miguel Neftalí

; Chang Landa, Frankis Antonio

; Martínez-Garza, Cristina

Acta botánica mexicana

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2022, Nº 129 elocation e1925

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen: Antecedentes y Objetivos: La producción ganadera es la principal causa de destrucción del hábitat y de la extinción de especies a nivel mundial. Es también un fuerte contribuyente a las emisiones de gases de efecto invernadero. En Latinoamérica, la ganadería es la principal actividad económica de muchas comunidades rurales, por lo que establecer plantaciones de restauración en pastizales podría brindar servicios ecosistémicos con beneficios directos e indirectos sobre la producción de ganado. Los sistemas silvopastoriles alcanzan niveles de producción iguales o superiores a los sistemas convencionales y prolongan la vida útil de las tierras productivas. Este trabajo examina la integración de sistemas silvopastoriles con la restauración con árboles nativos de importancia económica y para la conservación. Nos referimos a estas parcelas como sistemas silvopastoriles enriquecidos (SSPE). Presentamos los resultados de las primeras etapas de establecimiento de estos sistemas que buscan mejorar los medios de vida de los ganaderos y a mantener la conectividad del paisaje, los servicios ecosistémicos y la conservación de especies de la selva tropical. Métodos: En 2016, establecimos SSPE en una parcela piloto en Los Tuxtlas, México, plantando 16 especies de árboles nativos y Leucaena esculenta (DC.) Benth. como árbol forrajero. Paralelamente, se condujeron talleres de alternativas ganaderas en el ejido de Balzapote para incrementar las posibilidades de incidencia social. Resultados clave: La sobrevivencia de los árboles plantados fue en promedio de 40.7%. La parcela demostrativa ha servido para acercar a los agricultores a diferentes alternativas más productivas. Observamos una reducción en los costos de mantenimiento debido a que los productores no dependen de insumos externos. Conclusiones: Como resultado de la implementación del SSPE, la producción ganadera mejoró, lo que resulta en una disminución en el uso de agroquímicos. Los SSPE brindan complejidad al paisaje que dará como resultado sistemas más resilientes frente al cambio climático.

Abstract: Background and Aims: Livestock production is the main cause of habitat destruction and species extinction worldwide. It is also a strong contributor to greenhouse gas emissions. In Latin America, cattle ranching is the main economic activity of many rural communities, so establishing restoration plantations in pastures could provide ecosystem services with direct and indirect benefits for cattle production. Silvopastoral systems reach production levels equal to or higher than conventional systems and prolong the useful life of productive land. This paper examines the integration of silvopastoral systems with restoration with native trees of economic and conservation importance. We refer to these plots as enriched silvopastoral systems (ESPS). We present the results of the first stages of establishment of these systems which seek to improve the livelihoods of ranchers and to maintain landscape connectivity, ecosystem services, and the conservation of tropical forest species. Methods: In 2016, we established ESPS in a pilot plot in Los Tuxtlas, Mexico, planting 16 native tree species and Leucaena esculenta (DC.) Benth. as a fodder tree. At the same time, workshops on livestock alternatives were held in the ejido of Balzapote to increase the possibilities of social incidence. Key results: The survival of the planted trees was on average 40.7%. The demonstration plot has served to bring farmers closer to different more productive alternatives. We observe a reduction in maintenance costs because the producers are not dependent on external supplies. Conclusions: As a result of the implementation of the ESPS, livestock production improved, resulting in a decrease in the use of agrochemicals. ESPS will bring complexity to the landscape resulting in more resilient systems in the face of climate change.

https://doi.org/10.21829/abm129.2022.1925

13.

Fast surveillance response reveals the introduction of a new yellow fever virus sub-lineage in 2021, in Minas Gerais, Brazil
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Andrade, Miguel Souza

; Campos, Fabrício Souza

; Oliveira, Cirilo Henrique de

; Oliveira, Ramon Silva

; Campos, Aline Alves Scarpellini

; Almeida, Marco Antônio Barreto de

; Fonseca, Vagner de Souza

; Simonini-Teixeira, Danilo

; Sevá, Anaiá da Paixão

; Temponi, Andrea Oliveira Dias

; Magalhães, Fernando Maria

; Chaves, Danielle Costa Capistrano

; Pereira, Maira Alves

; Lamounier, Ludmila Oliveira

; Menezes, Givaldo Gomes de

; Aquino-Teixeira, Sandy Micaele

; Gonçalves-dos-Santos, Maria Eduarda

; Bernal-Valle, Sofía

; Müller, Nicolas Felipe Drumm

; Cardoso, Jader da Cruz

; Santos, Edmilson dos

; Mares-Guia, Maria Angélica

; Albuquerque, George Rêgo

; Romano, Alessandro Pecego Martins

; Franco, Ana Cláudia

; Ribeiro, Bergmann Morais

; Roehe, Paulo Michel

; Abreu, Filipe Vieira Santos de

Memórias do Instituto Oswaldo Cruz

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2022, Volume 117 elocation e220127

Resumo: En | Texto: En | PDF: En

BACKGROUND In Brazil, the yellow fever virus (YFV) is maintained in a sylvatic cycle involving wild mosquitoes and non-human primates (NHPs). The virus is endemic to the Amazon region; however, waves of epidemic expansion reaching other Brazilian states sporadically occur, eventually causing spillovers to humans. OBJECTIVES To report a surveillance effort that led to the first confirmation of YFV in NHPs in the state of Minas Gerais (MG), Southeast region, in 2021. METHODS A surveillance network was created, encompassing the technology of smartphone applications and coordinated actions of several research institutions and health services to monitor and investigate NHP epizootics. FINDINGS When alerts were spread through the network, samples from NHPs were collected and YFV infection confirmed by reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and genome sequencing at an interval of only 10 days. Near-complete genomes were generated using the Nanopore MinION sequencer. Phylogenetic analysis indicated that viral genomes were related to the South American genotype I, clustering with a genome detected in the Amazon region (state of Pará) in 2017, named YFVPA/MG sub-lineage. Fast YFV confirmation potentialised vaccination campaigns. MAIN CONCLUSIONS A new YFV introduction was detected in MG 6 years after the beginning of the major outbreak reported in the state (2015-2018). The YFV strain was not related to the sub-lineages previously reported in MG. No human cases have been reported, suggesting the importance of coordinated surveillance of NHPs using available technologies and supporting laboratories to ensure a quick response and implementation of contingency measures to avoid YFV spillover to humans.

https://doi.org/10.1590/0074-02760220127

14.

Efectos a largo plazo de la COVID-19: una revisión de la literatura
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Gutiérrez Bautista, Deyanira

; Mosqueda Martínez, Edson Erivan

; Vilchis, Hiram Joaquín

; Morales Fernández, José Antonio

; Cruz Salgado, Alejandra Xóchitl

; Chávez Aguilar, José Enrique

; Ramírez Velázquez, Ikky Omar

; Perón Medina, Luis Ángel

; García Osorno, Zurisadai Raquel

; Vásquez Martínez, Leonardo Martín

; Valadez González, Yazmín

; Díaz Ramírez, Jorge Baruch

; Cortázar Maldonado, Luis Alberto

; Vite Velázquez, Xcarelt

; García León, Miguel Leonardo

; Bautista Carbajal, Patricia

; Ángel Ambrocio, Antonio Humberto

; Wong Chew, Rosa María

Acta médica Grupo Ángeles

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Set 2021, Volume 19 Nº 3 Páginas 421 - 428

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract: COVID-19 has a wide spectrum of clinical manifestations, at least 55 long-term effects have been found including signs, symptoms and clinical parameters. The clinical stages of the disease are divided into an acute phase of COVID-19, post-acute phase, and post-COVID-19 syndrome. These phases are characterized by the development of signs and symptoms from the date of onset of symptoms and extend up to 4 weeks, between 4 and 12 weeks and beyond 12 weeks respectively. The prevalence varies from 35% to 94%, prevailing in most studies above 80%, with fatigue, cough and dyspnea being the most prevalent.The pathophysiological mechanisms that explain the development of symptoms include viral persistence, immune alterations and inflammation, expected sequel of critical illness, and specific pathophysiological alteration of acute disease in each system. The complete spectrum of post-COVID syndrome is still unknown, although many of its clinical components have been identified, information is still lacking to recognize the exact moment to determine its duration.

Resumen: La COVID-19 tiene un amplio espectro de manifestaciones clínicas durante su curso y se han encontrado al menos 55 efectos a largo plazo que incluyen signos, síntomas y parámetros clínicos. Las etapas clínicas de la enfermedad se dividen en la fase aguda, fase postaguda y síndrome post-COVID-19. Estas fases se caracterizan por el desarrollo de signos y síntomas desde el inicio hasta cuatro semanas, entre cuatro a 12 semanas y más allá de 12 semanas, respectivamente. La prevalencia de signos y síntomas varía desde 35% hasta 94%; en la mayoría de los estudios (80%) predominan la fatiga, tos y disnea. Los potenciales mecanismos fisiopatológicos que explican el desarrollo de los síntomas incluyen la persistencia viral, alteraciones inmunológicas e inflamación, secuelas esperadas de una enfermedad crítica y cambios fisiopatológicos específicos de la enfermedad aguda en cada sistema. Hasta el momento, se desconoce el espectro completo del síndrome post-COVID; a pesar de haber identificado muchos de sus componentes clínicos aún faltan datos para reconocer el tiempo exacto de duración.

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15.

Terapias farmacológicas para la COVID-19
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Morales Fernández, José Antonio

; Cruz Salgado, Alejandra Xóchitl

; Chávez Aguilar, José Enrique

; Mosqueda Martínez, Edson Erivan

; Gutiérrez Bautista, Deyanira

; Vilchis, Hiram Joaquín

; Ramírez Velázquez, Ikky Omar

; Perón Medina, Luis Ángel

; García Osorno, Zurisadai Raquel

; Vásquez Martínez, Leonardo Martín

; Valadez González, Yazmín

; Cortázar Maldonado, Luis Alberto

; Vite Velázquez, Xcarelt

; Ángel Ambrocio, Antonio Humberto

; García León, Miguel Leonardo

; Bautista Carbajal, Patricia

; Díaz Ramírez, Jorge Baruch

; Wong Chew, Rosa María

Acta médica Grupo Ángeles

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Set 2021, Volume 19 Nº 3 Páginas 408 - 420

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract: SARS-CoV-2 is the coronavirus that causes coronavirus disease 2019 (COVID-19), which is a disease of global concern and declared as a pandemic in 2020. For adequate control, personal protection measures have been taken and a great variety of drugs have been investigated to act in the pathogenic process to prevent the adhesion, replication and progression of the virus in the different stages of the disease, as well as the generation of effective neutralizing antibodies against it. The emergence of genetic variants has generated the need for advances in technologies for the development and research of new therapeutic targets. Currently, there is no specific drug for the pharmacological treatment of COVID-19, however, different drugs are used that have prevented the progression of the disease, recovery of illness, decreased mortality and increased survival.

Resumen: El virus SARS-CoV-2 es el coronavirus que causa la enfermedad por coronavirus 19 (COVID-19), ésta es una enfermedad de preocupación mundial y declarada pandemia en el 2020. Para el adecuado control se han tomado medidas de protección personal e investigado una gran variedad de medicamentos que actúen en las distintas etapas del proceso patogénico para evitar la adhesión, replicación y progresión del virus en los diferentes estadios de la enfermedad, así como la generación de anticuerpos neutralizantes efectivos contra la misma. El surgimiento de las variantes genéticas ha generado la necesidad del avance en las tecnologías para la elaboración e investigación de nuevos blancos terapéuticos. Actualmente, no se cuenta con ningún medicamento específico para el tratamiento farmacológico de la COVID-19; sin embargo, se utilizan diferentes medicamentos que han evitado la progresión de la enfermedad, la recuperación, así como la disminución de la mortalidad y aumento de la supervivencia.

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